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How can I upload a Custom Dose Response Dataset?

The Custom Dose Response Upload lets you upload your own processed dose-response tables and visualise them with the same modules used for datasets built directly in Mass Dynamics.

Steps to upload your Custom Dose Response Dataset

  1. Go to the Dataset Creation page and select Custom Dose Response Upload.
  2. Select the Intensity Dataset you want to link the upload to.
  3. As with a standard dose-response dataset, use "Filter Experiment Design by Column" to specify which samples in your experiment design the uploaded dataset corresponds to. This step is required so your upload behaves like a dataset processed directly on the platform: able to be filtered, compared, and visualised alongside the rest of your data.
  4. Upload your four tables: output_volcanoes.tsv, output_curves.tsv, input_drc.tsv, and runtime_metadata.tsv. Each table is checked against its required columns before the dataset is created.
  5. Your tables need to follow the same structure originally used for the 4-parameter log-logistic (LL4) regression from the standard Mass Dynamics dose-response workflow. If you used a different model, your tables still need to conform to this structure for the visualisations to work. You can download an example dataset here to use as a template.
  6. Once the dataset is uploaded and completes processing, get started exploring your dose-response curves and volcano plots!

You can download here a small example dataset with all the required tables for the upload.

 

Custom Dose Response Upload creation page.

Refer to the "About Custom Dose Response Upload" for detailed information about the meaning of the columns in dose response tables.